Product Information

CAS No.	220913-32-6
Product Name	Ar-67

Biological Targets

TOP1

Associated Conditions

neoplasm·cancer·myelodysplastic syndrome·gliosarcoma

* The information provided here is compiled from public sources and is for reference only.

Studies related to this compound and its mechanism of action

Validation of an HPLC method for analysis of DB-67 and its water soluble prodrug in mouse plasma.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences • Vol. 844, Issue 1 • 2006

PMID: 16860004 DOI: 10.1016/j.jchromb.2006.06.022

Molecular dynamics simulations and experimental studies of binding and mobility of 7-tert-butyldimethylsilyl-10-hydroxycamptothecin and its 20(S)-4-aminobutyrate ester in DMPC membranes.

Molecular pharmaceutics • Vol. 3, Issue 5 • 2006

PMID: 17009858 DOI: 10.1021/mp0600081

Silatecan DB-67 is a novel DNA topoisomerase I-targeted radiation sensitizer.

Molecular cancer therapeutics • Vol. 4, Issue 2 • 2005

PMID: 15713902

The effect of DB-67, a lipophilic camptothecin derivative, on topoisomerase I levels in non-small-cell lung cancer cells.

Cancer chemotherapy and pharmacology • Vol. 54, Issue 4 • 2004

PMID: 15197485 DOI: 10.1007/s00280-004-0804-3

Ar-67

CAS No.	220913-32-6
MDL No.	N/A
MF	C₂₆H₃₀N₂O₅Si
MW	478.60
InChI Key	XUSKJHCMMWAAHV-SANMLTNESA-N

CUSTOM SYNTHESIS PRECLINICAL SUPPORT

Pricing & Availability

Pack Size	Purity	Price	Availability	Action
-	-	On Request	On Request
Custom synthesis and bulk supply options are available upon request.

Product Information

CAS No.	220913-32-6
Product Name	Ar-67

Biological Targets

TOP1

Associated Conditions

neoplasm·cancer·myelodysplastic syndrome·gliosarcoma

* The information provided here is compiled from public sources and is for reference only.

Ar-67

Pricing & Availability

Product Information

Biological Profile

Properties

Biological Targets

Associated Conditions

Ar-67

Pricing & Availability

Product Information

Biological Profile

Properties

Biological Targets

Associated Conditions

Documentation

Ar-67

Pricing & Availability

Product Information

Biological Profile

Properties

Biological Targets

Associated Conditions

Related Articles

Validation of an HPLC method for analysis of DB-67 and its water soluble prodrug in mouse plasma.

Molecular dynamics simulations and experimental studies of binding and mobility of 7-tert-butyldimethylsilyl-10-hydroxycamptothecin and its 20(S)-4-aminobutyrate ester in DMPC membranes.

Silatecan DB-67 is a novel DNA topoisomerase I-targeted radiation sensitizer.

The effect of DB-67, a lipophilic camptothecin derivative, on topoisomerase I levels in non-small-cell lung cancer cells.

Similar Products

7-Ethyl-10-hydroxycamptothecin

Ar-67

Pricing & Availability

Product Information

Biological Profile

Properties

Biological Targets

Associated Conditions

Related Articles

Validation of an HPLC method for analysis of DB-67 and its water soluble prodrug in mouse plasma.

Molecular dynamics simulations and experimental studies of binding and mobility of 7-tert-butyldimethylsilyl-10-hydroxycamptothecin and its 20(S)-4-aminobutyrate ester in DMPC membranes.

Silatecan DB-67 is a novel DNA topoisomerase I-targeted radiation sensitizer.

The effect of DB-67, a lipophilic camptothecin derivative, on topoisomerase I levels in non-small-cell lung cancer cells.

Similar Products

7-Ethyl-10-hydroxycamptothecin

Documentation