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Chemical structure of CAS 220913-32-6

Ar-67

CAS No.220913-32-6
MDL No.N/A
MFC26H30N2O5Si
MW478.60
InChI KeyXUSKJHCMMWAAHV-SANMLTNESA-N
CUSTOM SYNTHESISPRECLINICAL SUPPORT

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
- -On RequestOn Request
Custom synthesis and bulk supply options are available upon request.

Product Information

CAS No.220913-32-6
Product NameAr-67

Biological Targets

TOP1

Associated Conditions

neoplasm·cancer·myelodysplastic syndrome·gliosarcoma
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

Validation of an HPLC method for analysis of DB-67 and its water soluble prodrug in mouse plasma.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences • Vol. 844, Issue 1 • 2006
PMID: 16860004DOI: 10.1016/j.jchromb.2006.06.022

Molecular dynamics simulations and experimental studies of binding and mobility of 7-tert-butyldimethylsilyl-10-hydroxycamptothecin and its 20(S)-4-aminobutyrate ester in DMPC membranes.

Molecular pharmaceutics • Vol. 3, Issue 5 • 2006
PMID: 17009858DOI: 10.1021/mp0600081

Silatecan DB-67 is a novel DNA topoisomerase I-targeted radiation sensitizer.

Molecular cancer therapeutics • Vol. 4, Issue 2 • 2005
PMID: 15713902

The effect of DB-67, a lipophilic camptothecin derivative, on topoisomerase I levels in non-small-cell lung cancer cells.

Cancer chemotherapy and pharmacology • Vol. 54, Issue 4 • 2004
PMID: 15197485DOI: 10.1007/s00280-004-0804-3

Documentation

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