Product Information

Sobetirome is a diarylmethane compound.

CAS No.	211110-63-3
Product Name	Sobetirome

Associated Conditions

X-linked adrenoleukodystrophy·adrenomyeloneuropathy

* The information provided here is compiled from public sources and is for reference only.

Studies related to this compound and its mechanism of action

Chemical Activation of the Constitutive Androstane Receptor Leads to Activation of Oxidant-Induced Nrf2.

Toxicological sciences : an official journal of the Society of Toxicology • Vol. 167, Issue 1 • 2019

PMID: 30203046 PMC: PMC6317430 DOI: 10.1093/toxsci/kfy231

Activation of Nrf2 in the liver is associated with stress resistance mediated by suppression of the growth hormone-regulated STAT5b transcription factor.

PloS one • Vol. 13, Issue 8 • 2018

PMID: 30114225 PMC: PMC6095522 DOI: 10.1371/journal.pone.0200004

TRbeta is the critical thyroid hormone receptor isoform in T3-induced proliferation of hepatocytes and pancreatic acinar cells.

Journal of hepatology • Vol. 53, Issue 4 • 2010

PMID: 20638743 DOI: 10.1016/j.jhep.2010.04.028

Structural basis of GC-1 selectivity for thyroid hormone receptor isoforms.

BMC structural biology • Vol. 8 • 2008

PMID: 18237438 PMC: PMC2275733 DOI: 10.1186/1472-6807-8-8

Sobetirome

CAS No.	211110-63-3
MDL No.	N/A
MF	C₂₀H₂₄O₄
MW	328.40
InChI Key	QNAZTOHXCZPOSA-UHFFFAOYSA-N

CUSTOM SYNTHESIS PRECLINICAL SUPPORT

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Custom synthesis and bulk supply options are available upon request.

Product Information

Sobetirome is a diarylmethane compound.

CAS No.	211110-63-3
Product Name	Sobetirome

Associated Conditions

X-linked adrenoleukodystrophy·adrenomyeloneuropathy

* The information provided here is compiled from public sources and is for reference only.

Sobetirome

Pricing & Availability

Product Information

Biological Profile

Properties

Associated Conditions

Sobetirome

Pricing & Availability

Product Information

Biological Profile

Properties

Associated Conditions

Documentation

Sobetirome

Pricing & Availability

Product Information

Biological Profile

Properties

Associated Conditions

Related Articles

Chemical Activation of the Constitutive Androstane Receptor Leads to Activation of Oxidant-Induced Nrf2.

Activation of Nrf2 in the liver is associated with stress resistance mediated by suppression of the growth hormone-regulated STAT5b transcription factor.

TRbeta is the critical thyroid hormone receptor isoform in T3-induced proliferation of hepatocytes and pancreatic acinar cells.

Structural basis of GC-1 selectivity for thyroid hormone receptor isoforms.

Similar Products

(4-(4-Hydroxy-3-isopropyl-5-(4-nitrophenylethynyl)benzyl)-3,5-dimethylphenoxy)acetic acid

MB-07811 (VK-2809)

Abx-002

Sobetirome

Pricing & Availability

Product Information

Biological Profile

Properties

Associated Conditions

Related Articles

Chemical Activation of the Constitutive Androstane Receptor Leads to Activation of Oxidant-Induced Nrf2.

Activation of Nrf2 in the liver is associated with stress resistance mediated by suppression of the growth hormone-regulated STAT5b transcription factor.

TRbeta is the critical thyroid hormone receptor isoform in T3-induced proliferation of hepatocytes and pancreatic acinar cells.

Structural basis of GC-1 selectivity for thyroid hormone receptor isoforms.

Similar Products

(4-(4-Hydroxy-3-isopropyl-5-(4-nitrophenylethynyl)benzyl)-3,5-dimethylphenoxy)acetic acid

MB-07811 (VK-2809)

Abx-002

Documentation