HomeProductsBioactive CompoundsDNA Damage & RepairTopoisomeraseCositecan
Chemical structure of CAS 203923-89-1

Cositecan

In Stock•Starting at $385 for 5 mg•Purity ≥ 95%
CAS No.203923-89-1
MDL No.N/A
MFC25H28N2O4Si
MW448.60
InChI KeyPOADTFBBIXOWFJ-VWLOTQADSA-N
CUSTOM SYNTHESISPRECLINICAL SUPPORT

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
5 mg95%$385In Stock
10 mg95%$711In Stock
25 mg95%$1553In Stock
50 mg95%$2256In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

Cositecan is a pyranoindolizinoquinoline.

CAS No.203923-89-1
Product NameCositecan
Heavy Atom Count32Rotatable Bond Count4
Atom Stereo Count1Bond Stereo Count0
HBA6HBD1
TPSA81.420 ŲCharge0
Exact Mass448.18183Complexity1338.49
pKa11.433XLogP3.960

Related Articles

Studies related to this compound and its mechanism of action

Plasma and cerebrospinal fluid pharmacokinetic study of BNP1350 in nonhuman primates.

Cancer chemotherapy and pharmacology • Vol. 53, Issue 6 • 2004
PMID: 14997342DOI: 10.1007/s00280-004-0765-6

Characterization of protein kinase chk1 essential for the cell cycle checkpoint after exposure of human head and neck carcinoma A253 cells to a novel topoisomerase I inhibitor BNP1350.

Molecular pharmacology • Vol. 57, Issue 3 • 2000
PMID: 10692484DOI: 10.1124/mol.57.3.453

New highly lipophilic camptothecin BNP1350 is an effective drug in experimental human cancer.

International journal of cancer • Vol. 88, Issue 2 • 2000
PMID: 11004678DOI: 10.1002/1097-0215(20001015)88:2<260::aid-ijc18>3.0.co;2-q

Documentation

Similar Products