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Chemical structure of CAS 19685-09-7

10-Hydroxycamptothecin

In Stock•Starting at $6 for 100 mg•Purity ≥ 98%
CAS No.19685-09-7
MDL No.MFCD02093100
MFC20H16N2O5
MW364.40
InChI KeyHAWSQZCWOQZXHI-FQEVSTJZSA-N

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
100 mg98+%$6In Stock
250 mg98+%$8In Stock
1 g98+%$19In Stock
5 g98+%$76In Stock
25 g98+%$366In Stock
4*25 g98+%$1436In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

10-Hydroxycamptothecin is a pyranoindolizinoquinoline derivative.

CAS No.19685-09-7
Product Name10-Hydroxycamptothecin
Heavy Atom Count27Rotatable Bond Count1
Atom Stereo Count1Bond Stereo Count0
HBA7HBD2
TPSA101.650 ŲCharge0
Exact Mass364.10592Complexity1213.20
pKa8.663XLogP1.785

Related Articles

Studies related to this compound and its mechanism of action

[Cell cycle block and apoptosis in rabbit lens epithelial cells induced by hydroxycamptothecine].

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology • Vol. 38, Issue 3 • 2002
PMID: 11955322

Simultaneous determination of the carboxylate and lactone forms of 10-hydroxycamptothecin in human serum by restricted-access media high-performance liquid chromatography.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences • Vol. 772, Issue 2 • 2002
PMID: 12007763DOI: 10.1016/s1570-0232(02)00085-5

Anti-tumor efficacy of a novel antisense anti-MDM2 mixed-backbone oligonucleotide in human colon cancer models: p53-dependent and p53-independent mechanisms.

Molecular medicine (Cambridge, Mass.) • Vol. 8, Issue 4 • 2002
PMID: 12149568PMC: PMC2039984

Synthesis and biological evaluation of novel A-ring modified hexacyclic camptothecin analogues.

Journal of medicinal chemistry • Vol. 44, Issue 10 • 2001
PMID: 11334569DOI: 10.1021/jm0004751

Documentation

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