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Chemical structure of CAS 18865-38-8

Glycine xylidide

In Stock•Starting at $108 for 100 mg•Purity ≥ 98%
CAS No.18865-38-8
MDL No.MFCD05267700
MFC10H14N2O
MW178.23
InChI KeyIXYVBZOSGGJWCW-UHFFFAOYSA-N

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
100 mg98%$108In Stock
250 mg98%$213In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

Glycinexylidide is an amino acid amide formed from 2,6-dimethylaniline and glycine, serving as an active metabolite of lidocaine resulting from oxidative deethylation. It is used as an indicator of hepatic function and functions as a drug metabolite.

CAS No.18865-38-8
Product NameGlycine xylidide
Heavy Atom Count13Rotatable Bond Count2
Atom Stereo Count0Bond Stereo Count0
HBA2HBD2
TPSA55.120 ŲCharge0
Exact Mass178.11061Complexity300.45
pKa7.130XLogP1.201

Related Articles

Studies related to this compound and its mechanism of action

Differential effect of chronic renal failure on the pharmacokinetics of lidocaine in patients receiving and not receiving hemodialysis.

Clinical pharmacology and therapeutics • Vol. 80, Issue 6 • 2006
PMID: 17178261DOI: 10.1016/j.clpt.2006.08.020

Thrombosis as a conformational disease.

Haematologica • Vol. 90, Issue 2 • 2005
PMID: 15710578

Cytochrome P450 1A2 is a major determinant of lidocaine metabolism in vivo: effects of liver function.

Clinical pharmacology and therapeutics • Vol. 75, Issue 1 • 2004
PMID: 14749694DOI: 10.1016/j.clpt.2003.09.007

Propofol does not inhibit lidocaine metabolism during epidural anesthesia.

Anesthesia and analgesia • Vol. 99, Issue 4 • 2004
PMID: 15385363DOI: 10.1213/01.ANE.0000131508.39939.86

Documentation

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