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Chemical structure of CAS 1809336-39-7

DS-3201b

CAS No.1809336-39-7
MDL No.MFCD31692361
MFC26H34ClN3O4
MW488.00
InChI KeySSDRNUPMYCFXGM-ZZHSESOFSA-N

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Product Information

CAS No.1809336-39-7
Product NameDS-3201b

Associated Conditions

neoplasm·lymphoma·breast cancer·non-Hodgkins lymphoma·hepatocellular carcinoma·
* The information provided here is compiled from public sources and is for reference only.

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Studies related to this compound and its mechanism of action

Valemetostat: First approval as a dual inhibitor of EZH1/2 to treat adult T-cell leukemia/lymphoma.

Drug discoveries & therapeutics • Vol. 16, Issue 6 • 2022
PMID: 36310058DOI: 10.5582/ddt.2022.01085

Targeting Excessive EZH1 and EZH2 Activities for Abnormal Histone Methylation and Transcription Network in Malignant Lymphomas.

Cell reports • Vol. 29, Issue 8 • 2019
PMID: 31747604DOI: 10.1016/j.celrep.2019.10.083

Novel orally bioavailable EZH1/2 dual inhibitors with greater antitumor efficacy than an EZH2 selective inhibitor.

Cancer science • Vol. 108, Issue 10 • 2017
PMID: 28741798PMC: PMC5623739DOI: 10.1111/cas.13326

Targeting EZH2 in cancer.

Nature medicine • Vol. 22, Issue 2 • 2016
PMID: 26845405PMC: PMC4918227DOI: 10.1038/nm.4036

Documentation

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