| CAS No. | 175414-77-4 |
|---|---|
| MDL No. | N/A |
| MF | C18H19N5O4S |
| MW | 401.40 |
| InChI Key | XZAFZXJXZHRNAQ-STQMWFEESA-N |
| Pack Size | Purity | Price | Availability | Action |
|---|---|---|---|---|
| 1 mg | To Be Confirmed | $99 | In Stock | |
| 5 mg | To Be Confirmed | $269 | In Stock | |
| 10 mg | To Be Confirmed | $428 | In Stock | |
| 25 mg | To Be Confirmed | $860 | In Stock | |
| 50 mg | To Be Confirmed | $1375 | In Stock | |
| 100 mg | To Be Confirmed | $2198 | In Stock | |
| Custom synthesis and bulk supply options are available upon request. | ||||
Vosaroxin is a 1,8-naphthyridin-4(1H)-one derivative substituted at positions 1, 3, and 7 with 1,3-thiazol-2-yl, carboxy, and (3S,4S)-3-methoxy-4-(methylamino)pyrrolidin-1-yl groups, respectively. It acts as a topoisomerase II inhibitor, inducing site-selective double-strand DNA breaks and triggering apoptosis in cancer cells. It functions as an antineoplastic agent, intercalator, apoptosis inducer, and radiosensitizing agent. It belongs to 1,3-thiazoles, monocarboxylic acids, 1,8-naphthyridine derivatives, pyrrolidines, secondary amino compounds, ethers, cyclic ketones, and quinolones.
| CAS No. | 175414-77-4 |
|---|---|
| Product Name | Vosaroxin |
| Heavy Atom Count | 28 | Rotatable Bond Count | 5 |
| Atom Stereo Count | 2 | Bond Stereo Count | 0 |
| HBA | 9 | HBD | 2 |
| TPSA | 109.580 Ų | Charge | 0 |
| Exact Mass | 401.11578 | Complexity | 1069.51 |
| pKa | 3.515 | XLogP | 0.963 |
