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Chemical structure of CAS 173334-57-1

Aliskiren

CAS No.173334-57-1
MDL No.MFCD09839018
MFC30H53N3O6
MW551.80
InChI KeyUXOWGYHJODZGMF-QORCZRPOSA-N
CUSTOM SYNTHESISPRECLINICAL SUPPORT

Pricing & Availability

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Custom synthesis and bulk supply options are available upon request.

Product Information

Aliskiren is a monomethoxybenzene with a 3-methoxypropoxy group at the 2-position and a multi-substituted branched alkyl group at the 4-position. It functions as an antihypertensive agent and is also a monocarboxylic acid amide.

CAS No.173334-57-1
Product NameAliskiren

Biological Targets

REN

Associated Conditions

hypertension·atrial fibrillation·diabetes mellitus·chronic kidney disease·essential hypertension·
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

Gateways to clinical trials.

Methods and findings in experimental and clinical pharmacology • Vol. 26, Issue 4 • 2004
PMID: 15319808

Blood pressure lowering in essential hypertension with an oral renin inhibitor, aliskiren.

Hypertension (Dallas, Tex. : 1979) • Vol. 42, Issue 6 • 2003
PMID: 14597641DOI: 10.1161/01.HYP.0000101688.17370.87

Structure-based design of aliskiren, a novel orally effective renin inhibitor.

Biochemical and biophysical research communications • Vol. 308, Issue 4 • 2003
PMID: 12927775DOI: 10.1016/s0006-291x(03)01451-7

Potential of renin inhibition in cardiovascular disease.

Journal of the renin-angiotensin-aldosterone system : JRAAS • Vol. 4, Issue 1 • 2003
PMID: 12692747DOI: 10.3317/jraas.2003.008

Documentation

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