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Chemical structure of CAS 1638250-96-0

Etc-159

CAS No.1638250-96-0
MDL No.MFCD29472267
MFC19H17N7O3
MW391.40
InChI KeyQTRXIFVSTWXRJJ-UHFFFAOYSA-N
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Product Information

CAS No.1638250-96-0
Product NameEtc-159

Associated Conditions

neoplasm
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

Porcupine inhibitors LGK-974 and ETC-159 inhibit Wnt/β-catenin signaling and result in inhibition of the fibrosis.

Toxicology in vitro : an international journal published in association with BIBRA • Vol. 104 • 2025
PMID: 39647516DOI: 10.1016/j.tiv.2024.105986

Scaffold Hopping and Optimization of Maleimide Based Porcupine Inhibitors.

Journal of medicinal chemistry • Vol. 60, Issue 15 • 2017
PMID: 28671458DOI: 10.1021/acs.jmedchem.7b00662

Wnt addiction of genetically defined cancers reversed by PORCN inhibition.

Oncogene • Vol. 35, Issue 17 • 2016
PMID: 26257057PMC: PMC4650263DOI: 10.1038/onc.2015.280

The use of porcupine inhibitors to target Wnt-driven cancers.

Bioorganic & medicinal chemistry letters • Vol. 25, Issue 23 • 2015
PMID: 26522946DOI: 10.1016/j.bmcl.2015.10.032

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