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Chemical structure of CAS 1633666-49-5

Nizubaglustat

CAS No.1633666-49-5
MDL No.N/A
MFC24H32FNO5
MW433.50
InChI KeyIRIRASPSMMWZOM-CJRSTVEYSA-N
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Product Information

CAS No.1633666-49-5
Product NameNizubaglustat

Associated Conditions

Niemann-Pick disease type C
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

First-in-human single-dose study of nizubaglustat, a dual inhibitor of ceramide glucosyltransferase and non-lysosomal glucosylceramidase: Safety, tolerability, pharmacokinetics, and pharmacodynamics of single ascending and multiple doses in healthy adults.

Molecular genetics and metabolism • Vol. 141, Issue 1 • 2024
PMID: 38113551DOI: 10.1016/j.ymgme.2023.108113

Identification and development of biphenyl substituted iminosugars as improved dual glucosylceramide synthase/neutral glucosylceramidase inhibitors.

Journal of medicinal chemistry • Vol. 57, Issue 21 • 2014
PMID: 25250725DOI: 10.1021/jm501181z

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