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Chemical structure of CAS 146062-49-9

Mitoglitazone

In Stock•Starting at $50 for 25 mg•Purity ≥ 97%
CAS No.146062-49-9
MDL No.MFCD00916084
MFC19H18N2O4S
MW370.40
InChI KeyIRNJSRAGRIZIHD-UHFFFAOYSA-N
CUSTOM SYNTHESISPRECLINICAL SUPPORT→

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
25 mg97%$50In Stock
50 mg97%$97In Stock
100 mg97%$190In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

5-[[4-[2-(5-ethyl-2-pyridinyl)-2-oxoethoxy]phenyl]methyl]thiazolidine-2,4-dione is an aromatic ether.

CAS No.146062-49-9
Product NameMitoglitazone

Associated Conditions

type 2 diabetes mellitus·Alzheimer disease
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

Key features of inhibitor binding to the human mitochondrial pyruvate carrier hetero-dimer.

Molecular metabolism • Vol. 60 • 2022
PMID: 35278701PMC: PMC8968063DOI: 10.1016/j.molmet.2022.101469

An evaluation of MSDC-0160, a prototype mTOT modulating insulin sensitizer, in patients with mild Alzheimer's disease.

Current Alzheimer research • Vol. 11, Issue 6 • 2014
PMID: 24931567PMC: PMC4153084DOI: 10.2174/1567205011666140616113406

Correlation between activation of PPARγ and resistin downregulation in a mouse adipocyte cell line by a series of thiazolidinediones.

Toxicology in vitro : an international journal published in association with BIBRA • Vol. 27, Issue 5 • 2013
PMID: 23563205DOI: 10.1016/j.tiv.2013.03.011

Thiazolidinediones are acute, specific inhibitors of the mitochondrial pyruvate carrier.

Proceedings of the National Academy of Sciences of the United States of America • Vol. 110, Issue 14 • 2013
PMID: 23513224PMC: PMC3619368DOI: 10.1073/pnas.1303360110

Documentation

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