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Chemical structure of CAS 145435-72-9

Gamithromycin

In Stock•Starting at $9 for 1 mg•Purity ≥ 95%
CAS No.145435-72-9
MDL No.MFCD09954125
MFC40H76N2O12
MW777.00
InChI KeyVWAMTBXLZPEDQO-UZSBJOJWSA-N
CUSTOM SYNTHESISPRECLINICAL SUPPORT→

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
1 mg95%$9In Stock
5 mg95%$18In Stock
10 mg95%$26In Stock
50 mg95%$31In Stock
100 mg95%$46In Stock
250 mg95%$62In Stock
1 g95%$118In Stock
5 g95%$579In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

Gamithromycin is a macrolide antibiotic with the formula C40H76N2O12. It treats bovine respiratory disease caused by Mannheimia haemolytica, Pasteurella multocida, Histophilus somni, and Mycoplasma bovis in beef and non-lactating dairy cattle. It is also licensed in Europe for treating footrot in sheep caused by Dichelobacter nodosus and Fusobacterium nodosus. It functions as an antibacterial drug and protein synthesis inhibitor, and is a macrolide antibiotic and monosaccharide derivative.

CAS No.145435-72-9
Product NameGamithromycin
Heavy Atom Count54Rotatable Bond Count9
Atom Stereo Count18Bond Stereo Count0
HBA14HBD5
TPSA180.080 ŲCharge0
Exact Mass776.53983Complexity1175.73
pKa11.433XLogP2.681

Related Articles

Studies related to this compound and its mechanism of action

Modulation by gamithromycin and ketoprofen of in vitro and in vivo porcine lipopolysaccharide-induced inflammation.

Veterinary immunology and immunopathology • Vol. 168, Issue 3-4 • 2015
PMID: 26547885DOI: 10.1016/j.vetimm.2015.09.014

In vitro pharmacodynamics of gamithromycin against Mycoplasma mycoides subspecies mycoides Small Colony.

Veterinary journal (London, England : 1997) • Vol. 197, Issue 3 • 2013
PMID: 23810743DOI: 10.1016/j.tvjl.2013.05.025

Pharmacokinetics of gamithromycin after intravenous and subcutaneous administration in broiler chickens.

Poultry science • Vol. 92, Issue 6 • 2013
PMID: 23687147DOI: 10.3382/ps.2012-02932

Plasma pharmacokinetics, pulmonary distribution, and in vitro activity of gamithromycin in foals.

Journal of veterinary pharmacology and therapeutics • Vol. 35, Issue 1 • 2012
PMID: 21443748DOI: 10.1111/j.1365-2885.2011.01292.x

Documentation

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