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Chemical structure of CAS 1448671-31-5

Azd-3965

CAS No.1448671-31-5
MDL No.MFCD28963899
MFC21H24F3N5O5S
MW515.50
InChI KeyPRNXOFBDXNTIFG-FQEVSTJZSA-N
CUSTOM SYNTHESIS

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Product Information

CAS No.1448671-31-5
Product NameAzd-3965
Heavy Atom Count35Rotatable Bond Count4
Atom Stereo Count1Bond Stereo Count0
HBA9HBD2
TPSA122.450 ŲCharge0
Exact Mass515.14502Complexity1446.59
pKa7.130XLogP2.122

Related Articles

Studies related to this compound and its mechanism of action

Autophagy induces mTOR-dependent glucose uptake and mTOR-independent lactate utilization in cadmium-treated A549 cells.

Toxicology in vitro : an international journal published in association with BIBRA • Vol. 86 • 2023
PMID: 36336208DOI: 10.1016/j.tiv.2022.105513

The IUPHAR Guide to Immunopharmacology: connecting immunology and pharmacology.

Immunology • Vol. 160, Issue 1 • 2020
PMID: 32020584PMC: PMC7160657DOI: 10.1111/imm.13175

Monocarboxylate transporter 1 blockade with AZD3965 inhibits lipid biosynthesis and increases tumour immune cell infiltration.

British journal of cancer • Vol. 122, Issue 6 • 2020
PMID: 31937921PMC: PMC7078321DOI: 10.1038/s41416-019-0717-x

Detection of Chemical Engagement of Solute Carrier Proteins by a Cellular Thermal Shift Assay.

ACS chemical biology • Vol. 13, Issue 6 • 2018
PMID: 29851333PMC: PMC6067815DOI: 10.1021/acschembio.8b00270

Documentation

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