Pharmacokinetics, pharmacodynamics, and tolerability of subcutaneous administration of a novel glycoprotein IIb/IIIa inhibitor, RUC-4, in patients with ST-segment elevation myocardial infarction.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology • Vol. 17, Issue 5 • 2021
Preclinical Studies of RUC-4, a Novel Platelet αIIbβ3 Antagonist, in Non-Human Primates and With Human Platelets.
Journal of clinical and translational science • Vol. 3, Issue 2-3 • 2019
RUC-4: a novel αIIbβ3 antagonist for prehospital therapy of myocardial infarction.
Arteriosclerosis, thrombosis, and vascular biology • Vol. 34, Issue 10 • 2014
A novel class of ion displacement ligands as antagonists of the αIIbβ3 receptor that limit conformational reorganization of the receptor.
Bioorganic & medicinal chemistry letters • Vol. 24, Issue 4 • 2014