Selinexor is a triazole compound with a 1H-1,2,4-triazole core substituted at positions 1 and 3 by (1Z)-3-oxo-3-[2-(pyrazin-2-yl)hydrazinyl]prop-1-en-1-yl and 3,5-bis(trifluoromethyl)phenyl groups, respectively. It is a prescription medicine approved for treating adult patients with relapsed or refractory diffuse large B-cell lymphoma. It functions as an exportin 1 inhibitor, antineoplastic agent, anti-inflammatory agent, and apoptosis inducer. It belongs to the classes of (trifluoromethyl)benzenes, triazoles, pyrazines, enamides, and hydrazides.
