| CAS No. | 136572-09-3 |
|---|---|
| MDL No. | N/A |
| MF | C33H45ClN4O9 |
| MW | 677.20 |
| InChI Key | KLEAIHJJLUAXIQ-JDRGBKBRSA-N |
| Pack Size | Purity | Price | Availability | Action |
|---|---|---|---|---|
| - | - | On Request | On Request | |
| Custom synthesis and bulk supply options are available upon request. | ||||
Irinotecan hydrochloride hydrate is the trihydrate form of irinotecan hydrochloride. Onivyde is used in combination with fluorouracil and leucovorin for the treatment of metastatic pancreatic adenocarcinoma following gemcitabine-based therapy. It is hydrolyzed to its active metabolite, SN-38, which is ~1000 times more active. It functions as a DNA topoisomerase inhibitor, antineoplastic agent, apoptosis inducer, and prodrug. It contains irinotecan hydrochloride (anhydrous).
| CAS No. | 136572-09-3 |
|---|---|
| Product Name | Camptosar |
| Heavy Atom Count | 47 | Rotatable Bond Count | 4 |
| Atom Stereo Count | 1 | Bond Stereo Count | 0 |
| HBA | 9 | HBD | 1 |
| TPSA | 208.700 Ų | Charge | 0 |
| Exact Mass | 676.28751 | Complexity | 1699.84 |
| pKa | 11.433 | XLogP | 2.039 |
