HomeProductsBioactive CompoundsProtein Kinase TargetsBTKTirabrutinib
Chemical structure of CAS 1351636-18-4

Tirabrutinib

In Stock•Starting at $25 for 1 mg•Purity ≥ 98%
CAS No.1351636-18-4
MDL No.MFCD28386296
MFC25H22N6O3
MW454.50
InChI KeySEJLPXCPMNSRAM-GOSISDBHSA-N

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
1 mg98+%$25In Stock
5 mg98+%$35In Stock
10 mg98+%$56In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

Tirabrutinib is an orally available BTK inhibitor with potential antineoplastic activity. It covalently binds to BTK in B cells, blocking B cell receptor signaling and inhibiting B cell development, thereby suppressing the proliferation of B cell malignancies.

CAS No.1351636-18-4
Product NameTirabrutinib

Biological Targets

BTK

Associated Conditions

neoplasm·rheumatoid arthritis·non-Hodgkins lymphoma·chronic idiopathic urticaria·Sjogren syndrome·
* The information provided here is compiled from public sources and is for reference only.

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Studies related to this compound and its mechanism of action

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A phase 1 clinical trial of the selective BTK inhibitor ONO/GS-4059 in relapsed and refractory mature B-cell malignancies.

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Documentation

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