HomeProductsBioactive CompoundsEndocrine & Hormonal TargetsGHSRPF-5190457
Chemical structure of CAS 1334782-79-4

PF-5190457

CAS No.1334782-79-4
MDL No.N/A
MFC29H32N6OS
MW512.70
InChI KeyZIUDADZJCKGWKR-AREMUKBSSA-N

Pricing & Availability

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Product Information

CAS No.1334782-79-4
Product NamePF-5190457

Biological Targets

GHSR

Associated Conditions

alcohol-related disorders·alcohol drinking·alcohol dependence·type 2 diabetes mellitus
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

Pharmacological characterization of the first in class clinical candidate PF-05190457: a selective ghrelin receptor competitive antagonist with inverse agonism that increases vagal afferent firing and glucose-dependent insulin secretion ex vivo.

British journal of pharmacology • Vol. 173, Issue 9 • 2016
PMID: 26784385PMC: PMC4831304DOI: 10.1111/bph.13439

Discovery of PF-5190457, a Potent, Selective, and Orally Bioavailable Ghrelin Receptor Inverse Agonist Clinical Candidate.

ACS medicinal chemistry letters • Vol. 5, Issue 5 • 2014
PMID: 24900864PMC: PMC4027753DOI: 10.1021/ml400473x

Documentation

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