HomeProductsBioactive CompoundsMetabolic EnzymesAldose ReductaseZenarestat
Chemical structure of CAS 112733-06-9

Zenarestat

In Stock•Starting at $159 for 1 mg
CAS No.112733-06-9
MDL No.N/A
MFC17H11BrClFN2O4
MW441.60
InChI KeySXONDGSPUVNZLO-UHFFFAOYSA-N

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
1 mgTo Be Confirmed$159In Stock
2 mgTo Be Confirmed$234In Stock
5 mgTo Be Confirmed$442In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

CAS No.112733-06-9
Product NameZenarestat
Heavy Atom Count26Rotatable Bond Count4
Atom Stereo Count0Bond Stereo Count0
HBA5HBD1
TPSA81.300 ŲCharge0
Exact Mass439.95747Complexity1155.93
pKa2.768XLogP2.851

Related Articles

Studies related to this compound and its mechanism of action

Aldose reductase inhibitors for the treatment of diabetic polyneuropathy.

The Cochrane database of systematic reviews • Vol. 2007, Issue 4 • 2007
PMID: 17943821PMC: PMC8406996DOI: 10.1002/14651858.CD004572.pub2

Role of aldose reductase and oxidative damage in diabetes and the consequent potential for therapeutic options.

Endocrine reviews • Vol. 26, Issue 3 • 2005
PMID: 15814847DOI: 10.1210/er.2004-0028

Discovery of 3-[(4,5,7-trifluorobenzothiazol-2-yl)methyl]indole-N-acetic acid (lidorestat) and congeners as highly potent and selective inhibitors of aldose reductase for treatment of chronic diabetic complications.

Journal of medicinal chemistry • Vol. 48, Issue 9 • 2005
PMID: 15857120DOI: 10.1021/jm0492094

Documentation