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Chemical structure of CAS 111974-69-7

Quetiapine

CAS No.111974-69-7
MDL No.MFCD00866699
MFC21H25N3O2S
MW383.50
InChI KeyURKOMYMAXPYINW-UHFFFAOYSA-N
CUSTOM SYNTHESISPRECLINICAL SUPPORT

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
- -On RequestOn Request
Custom synthesis and bulk supply options are available upon request.

Product Information

Quetiapine is a dibenzothiazepine, N-alkylpiperazine, and N-arylpiperazine. It functions as a serotonergic, dopaminergic, histamine, and adrenergic antagonist, and is a second-generation antipsychotic.

CAS No.111974-69-7
Product NameQuetiapine

Biological Targets

DRD2·HTR2A·HTR2C

Associated Conditions

multiple sclerosis·obsessive-compulsive disorder·depressive disorder·Anxiety·cocaine dependence·
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

Enhanced neurotensin neurotransmission is involved in the clinically relevant behavioral effects of antipsychotic drugs: evidence from animal models of sensorimotor gating.

The Journal of neuroscience : the official journal of the Society for Neuroscience • Vol. 21, Issue 2 • 2001
PMID: 11160439PMC: PMC6763810DOI: 10.1523/JNEUROSCI.21-02-00601.2001

Atypical antipsychotics: new directions and new challenges in the treatment of schizophrenia.

Annual review of medicine • Vol. 52 • 2001
PMID: 11160792DOI: 10.1146/annurev.med.52.1.503

Consistency of atypical antipsychotic superiority to placebo in recent clinical trials.

Biological psychiatry • Vol. 49, Issue 1 • 2001
PMID: 11163781DOI: 10.1016/s0006-3223(00)00973-2

The effects of concomitant phenytoin administration on the steady-state pharmacokinetics of quetiapine.

Journal of clinical psychopharmacology • Vol. 21, Issue 1 • 2001
PMID: 11199955DOI: 10.1097/00004714-200102000-00016

Documentation

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