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Chemical structure of CAS 1095004-78-6

Azd-7624

In Stock•Starting at $188 for 1 mg
CAS No.1095004-78-6
MDL No.N/A
MFC27H30FN5O3
MW491.60
InChI KeyNNKPHNTWNILINE-UHFFFAOYSA-N

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
1 mgTo Be Confirmed$188In Stock
5 mgTo Be Confirmed$454In Stock
10 mgTo Be Confirmed$729In Stock
25 mgTo Be Confirmed$1222In Stock
50 mgTo Be Confirmed$1744In Stock
100 mgTo Be Confirmed$2385In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

CAS No.1095004-78-6
Product NameAzd-7624
Heavy Atom Count36Rotatable Bond Count10
Atom Stereo Count0Bond Stereo Count0
HBA7HBD3
TPSA97.280 ŲCharge0
Exact Mass491.23327Complexity1347.48
pKa9.247XLogP3.272

Related Articles

Studies related to this compound and its mechanism of action

The discovery and evaluation of 3-amino-2(1H)-pyrazinones as a novel series of selective p38α MAP kinase inhibitors.

Bioorganic & medicinal chemistry letters • Vol. 30, Issue 18 • 2020
PMID: 32717614DOI: 10.1016/j.bmcl.2020.127412

The IUPHAR Guide to Immunopharmacology: connecting immunology and pharmacology.

Immunology • Vol. 160, Issue 1 • 2020
PMID: 32020584PMC: PMC7160657DOI: 10.1111/imm.13175

The development of AZD7624 for prevention of exacerbations in COPD: a randomized controlled trial.

International journal of chronic obstructive pulmonary disease • Vol. 13 • 2018
PMID: 29628759PMC: PMC5877500DOI: 10.2147/COPD.S150576

AZD7624, an Inhaled p38 Inhibitor, Demonstrates Local Lung Inhibition of LPS-Induced TNF with Minimal Systemic Exposure.

The Journal of pharmacology and experimental therapeutics • Vol. 365, Issue 3 • 2018
PMID: 29549158DOI: 10.1124/jpet.117.246132

Documentation