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Chemical structure of CAS 106650-56-0

Sibutramine

CAS No.106650-56-0
MDL No.N/A
MFC17H26ClN
MW279.80
InChI KeyUNAANXDKBXWMLN-UHFFFAOYSA-N
CUSTOM SYNTHESISPRECLINICAL SUPPORT

Pricing & Availability

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Product Information

Sibutramine is an organochlorine, tertiary amino compound with roles as an anti-obesity agent and serotonin uptake inhibitor.

CAS No.106650-56-0
Product NameSibutramine

Biological Targets

SLC6A4·SLC6A3·SLC6A2

Associated Conditions

obesity
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

Potent inhibition of cytochrome P450 2B6 by sibutramine in human liver microsomes.

Chemico-biological interactions • Vol. 205, Issue 1 • 2013
PMID: 23777987DOI: 10.1016/j.cbi.2013.06.006

The use of sibutramine in the management of obesity and related disorders: an update.

Vascular health and risk management • Vol. 5, Issue 1 • 2009
PMID: 19475780PMC: PMC2686261DOI: 10.2147/vhrm.s4027

Sibutramine: current status as an anti-obesity drug and its future perspectives.

Expert opinion on pharmacotherapy • Vol. 9, Issue 12 • 2008
PMID: 18671470DOI: 10.1517/14656566.9.12.2161

Open channel block of A-type, kv4.3, and delayed rectifier K+ channels, Kv1.3 and Kv3.1, by sibutramine.

The Journal of pharmacology and experimental therapeutics • Vol. 321, Issue 2 • 2007
PMID: 17312186DOI: 10.1124/jpet.106.117747

Documentation

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