Nomilin is a limonoid with the formula C28H34O9, commonly found in edible citrus fruits such as lemons, limes, oranges, and grapefruits. It exhibits various biological and pharmacological activities, including anticancer, anti-inflammatory, antiobesity, and antiviral effects. Nomilin acts as a pregnane X receptor agonist, geroprotector, anti-inflammatory agent, antioxidant, skin lightening agent, anti-obesity agent, hypoglycemic agent, angiogenesis inhibitor, apoptosis inducer, anti-HIV-1 agent, plant metabolite, antineoplastic agent, and immunomodulator. It is classified as a limonoid, organic heteropentacyclic compound, lactone, furan, epoxide, acetate ester, and pentacyclic triterpenoid.