Tak-733
| CAS No. | 1035555-63-5 |
|---|---|
| MDL No. | MFCD24386349 |
| MF | C17H15F2IN4O4 |
| MW | 504.23 |
| InChI Key | RCLQNICOARASSR-SECBINFHSA-N |
Pricing & Availability
| Pack Size | Purity | Price | Availability | Action |
|---|---|---|---|---|
| - | - | On Request | On Request | |
| Custom synthesis and bulk supply options are available upon request. | ||||
Product Information
TAK-733 is a pyridopyrimidine compound with a pyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione core substituted at positions 3, 5, 6, and 8 by (2R)-2,3-dihydroxypropyl, (2-fluoro-4-iodophenyl)amino, fluoro, and methyl groups, respectively. It is a non-ATP competitive allosteric inhibitor of MEK1/2, acting as an EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor, apoptosis inducer, antineoplastic agent, and anti-inflammatory agent. It is also an organoiodine compound, a substituted aniline, a diol, a secondary alcohol, a primary alcohol, and a secondary amino compound.
| CAS No. | 1035555-63-5 |
|---|---|
| Product Name | Tak-733 |
Biological Targets
MAP2K1·MAP2K2
Associated Conditions
cancer·metastatic melanoma·neoplasm·Familial adenomatous polyposis
* The information provided here is compiled from public sources and is for reference only.