Inhibition of hepatitis C virus replication by GS-6620, a potent C-nucleoside monophosphate prodrug.
Antimicrobial agents and chemotherapy • Vol. 58, Issue 4 • 2014
Imidazopyridazine hepatitis C virus polymerase inhibitors. Structure-activity relationship studies and the discovery of a novel, traceless prodrug mechanism.
Journal of medicinal chemistry • Vol. 57, Issue 5 • 2014
In vitro efficacy of approved and experimental antivirals against novel genotype 3 hepatitis C virus subgenomic replicons.
Antiviral research • Vol. 100, Issue 2 • 2013
The HCV non-nucleoside inhibitor Tegobuvir utilizes a novel mechanism of action to inhibit NS5B polymerase function.
PloS one • Vol. 7, Issue 6 • 2012