SM-164
In Stock•Starting at $91 for 1 mg•Purity ≥ 98%
| CAS No. | 957135-43-2 |
|---|---|
| MDL No. | N/A |
| MF | C62H84N14O6 |
| MW | 1121.40 |
| InChI Key | LGYDZXNSSLRFJS-IOQQVAQYSA-N |
Pricing & Availability
| Pack Size | Purity | Price | Availability | Action |
|---|---|---|---|---|
| 1 mg | 98% | $91 | In Stock | |
| 5 mg | 98% | $268 | In Stock | |
| 10 mg | 98% | $453 | In Stock | |
| 25 mg | 98% | $903 | In Stock | |
| Custom synthesis and bulk supply options are available upon request. | ||||
Product Information
SM-164 is a potent, cell-permeable, bivalent Smac mimetic that binds to XIAP, cIAP-1, and cIAP-2 with Ki values of 0.56 nM, 0.31 nM, and 1.1 nM, respectively. It induces apoptosis and tumor regression in cancer xenograft models and functions as a radiosensitizing agent, antineoplastic agent, and apoptosis inducer. It is a member of triazoles, benzenes, secondary carboxamides, and organic heterobicyclic compounds.
| CAS No. | 957135-43-2 |
|---|---|
| Product Name | SM-164 |
| Heavy Atom Count | 82 | Rotatable Bond Count | 24 |
| Atom Stereo Count | 10 | Bond Stereo Count | 0 |
| HBA | 14 | HBD | 6 |
| TPSA | 242.500 Ų | Charge | 0 |
| Exact Mass | 1120.66983 | Complexity | 2721.87 |
| pKa | 5.875 | XLogP | 5.379 |