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Chemical structure of CAS 937782-05-3

Difamilast

CAS No.937782-05-3
MDL No.N/A
MFC23H24F2N2O5
MW446.40
InChI KeyVFBILHPIHUPBPZ-UHFFFAOYSA-N

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
- -On RequestOn Request
Custom synthesis and bulk supply options are available upon request.

Product Information

CAS No.937782-05-3
Product NameDifamilast

Biological Targets

PDE4A·PDE4D·PDE4B·PDE4C

Associated Conditions

atopic eczema
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

Pharmacological Profile of Difamilast, a Novel Selective Phosphodiesterase 4 Inhibitor, for Topical Treatment of Atopic Dermatitis.

The Journal of pharmacology and experimental therapeutics • Vol. 386, Issue 1 • 2023
PMID: 37041087DOI: 10.1124/jpet.123.001609

New molecules for atopic dermatitis treatment beyond biological therapy.

Current opinion in allergy and clinical immunology • Vol. 23, Issue 3 • 2023
PMID: 37185825DOI: 10.1097/ACI.0000000000000910

The IUPHAR Guide to Immunopharmacology: connecting immunology and pharmacology.

Immunology • Vol. 160, Issue 1 • 2020
PMID: 32020584PMC: PMC7160657DOI: 10.1111/imm.13175

OPA-15406, a novel, topical, nonsteroidal, selective phosphodiesterase-4 (PDE4) inhibitor, in the treatment of adult and adolescent patients with mild to moderate atopic dermatitis (AD): A phase-II randomized, double-blind, placebo-controlled study.

Journal of the American Academy of Dermatology • Vol. 75, Issue 2 • 2016
PMID: 27189825DOI: 10.1016/j.jaad.2016.04.001

Documentation