Pracinostat
| CAS No. | 929016-96-6 |
|---|---|
| MDL No. | N/A |
| MF | C20H30N4O2 |
| MW | 358.50 |
| InChI Key | JHDKZFFAIZKUCU-ZRDIBKRKSA-N |
Pricing & Availability
| Pack Size | Purity | Price | Availability | Action |
|---|---|---|---|---|
| - | - | On Request | On Request | |
| Custom synthesis and bulk supply options are available upon request. | ||||
Product Information
Pracinostat is a hydroxamic acid and an olefinic compound, specifically an N-hydroxyacrylamide substituted at position 3 with a 2-butyl-1-[2-(diethylamino)ethyl]-1H-benzimidazol-5-yl group (the E isomer). It is an orally available pan-histone deacetylase inhibitor with activity in the treatment of advanced solid tumours. It functions as an EC 3.5.1.98 (histone deacetylase) inhibitor, an antineoplastic agent, an apoptosis inducer, and an antimalarial. It is also a benzimidazole and a tertiary amino compound.
| CAS No. | 929016-96-6 |
|---|---|
| Product Name | Pracinostat |
| Heavy Atom Count | 26 | Rotatable Bond Count | 10 |
| Atom Stereo Count | 0 | Bond Stereo Count | 1 |
| HBA | 5 | HBD | 2 |
| TPSA | 70.390 Ų | Charge | 0 |
| Exact Mass | 358.23688 | Complexity | 747.59 |
| pKa | 7.130 | XLogP | 3.239 |