HomeProductsBioactive CompoundsProtein Kinase Targetsc-Met/HGFRGolvatinib
Chemical structure of CAS 928037-13-2

Golvatinib

CAS No.928037-13-2
MDL No.MFCD22124462
MFC33H37F2N7O4
MW633.70
InChI KeyUQRCJCNVNUFYDX-UHFFFAOYSA-N

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
- -On RequestOn Request
Custom synthesis and bulk supply options are available upon request.

Product Information

Golvatinib is an aromatic ether.

CAS No.928037-13-2
Product NameGolvatinib

Biological Targets

MET·KDR

Associated Conditions

cancer·head and neck squamous cell carcinoma·neoplasm·gastric cancer
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

Paracrine receptor activation by microenvironment triggers bypass survival signals and ALK inhibitor resistance in EML4-ALK lung cancer cells.

Clinical cancer research : an official journal of the American Association for Cancer Research • Vol. 18, Issue 13 • 2012
PMID: 22553343DOI: 10.1158/1078-0432.CCR-11-2972

Met kinase inhibitor E7050 reverses three different mechanisms of hepatocyte growth factor-induced tyrosine kinase inhibitor resistance in EGFR mutant lung cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research • Vol. 18, Issue 6 • 2012
PMID: 22317763DOI: 10.1158/1078-0432.CCR-11-1171

E7050: a dual c-Met and VEGFR-2 tyrosine kinase inhibitor promotes tumor regression and prolongs survival in mouse xenograft models.

Cancer science • Vol. 101, Issue 1 • 2010
PMID: 19832844PMC: PMC11159146DOI: 10.1111/j.1349-7006.2009.01343.x

Documentation