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Chemical structure of CAS 923287-50-7

Opicapone

CAS No.923287-50-7
MDL No.MFCD19443745
MFC15H10Cl2N4O6
MW413.20
InChI KeyASOADIZOVZTJSR-UHFFFAOYSA-N

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Product Information

Opicapone is an oxadiazole-containing ring system.

CAS No.923287-50-7
Product NameOpicapone

Biological Targets

COMT

Associated Conditions

Parkinson disease
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

In vitro effects of opicapone on activity of human UDP-glucuronosyltransferases isoforms.

Toxicology letters • Vol. 367 • 2022
PMID: 35810997DOI: 10.1016/j.toxlet.2022.07.003

Pharmacokinetics of opicapone, a third-generation COMT inhibitor, after single and multiple oral administration: A comparative study in the rat.

Toxicology and applied pharmacology • Vol. 323 • 2017
PMID: 28322896DOI: 10.1016/j.taap.2017.03.013

Opicapone as an adjunct to levodopa in patients with Parkinson's disease and end-of-dose motor fluctuations: a randomised, double-blind, controlled trial.

The Lancet. Neurology • Vol. 15, Issue 2 • 2016
PMID: 26725544DOI: 10.1016/S1474-4422(15)00336-1

Opicapone: A Review in Parkinson's Disease.

Drugs • Vol. 76, Issue 13 • 2016
PMID: 27498199DOI: 10.1007/s40265-016-0623-y

Documentation