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Chemical structure of CAS 91421-43-1

9-Aminocamptothecin

CAS No.91421-43-1
MDL No.MFCD00909855
MFC20H17N3O4
MW363.40
InChI KeyFUXVKZWTXQUGMW-FQEVSTJZSA-N
CUSTOM SYNTHESISPRECLINICAL SUPPORT

Pricing & Availability

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Product Information

9-Aminocamptothecin is a pyranoindolizinoquinoline.

CAS No.91421-43-1
Product Name9-Aminocamptothecin

Biological Targets

TOP1

Associated Conditions

ovarian cancer·gastric cancer·lymphoma·ovarian neoplasm·kidney cancer·
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

Pharmacological determinants of 9-aminocamptothecin cytotoxicity.

Clinical cancer research : an official journal of the American Association for Cancer Research • Vol. 7, Issue 1 • 2001
PMID: 11205905

Relation between 9-aminocamptothecin systemic exposure and tumor response in human solid tumor xenografts.

Clinical cancer research : an official journal of the American Association for Cancer Research • Vol. 7, Issue 2 • 2001
PMID: 11234891

Modulation of camptothecin analogs in the treatment of cancer: a review.

Anti-cancer drugs • Vol. 12, Issue 2 • 2001
PMID: 11261892DOI: 10.1097/00001813-200102000-00002

Circumvention of breast cancer resistance protein (BCRP)-mediated resistance to camptothecins in vitro using non-substrate drugs or the BCRP inhibitor GF120918.

Clinical cancer research : an official journal of the American Association for Cancer Research • Vol. 7, Issue 4 • 2001
PMID: 11309344

Documentation

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