Chemical structure of CAS 912999-49-6

Onalespib

CAS No.912999-49-6
MDL No.MFCD18633198
MFC24H31N3O3
MW409.50
InChI KeyIFRGXKKQHBVPCQ-UHFFFAOYSA-N
CUSTOM SYNTHESIS

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
- -On RequestOn Request
Custom synthesis and bulk supply options are available upon request.

Product Information

Onalespib is an isoindole in which the amino group is acylated by a 2,4-dihydroxy-5-isopropylbenzoyl group and position 5 of the isoindole moiety is substituted by a (4-methylpiperazin-1-yl)methyl group. It is a second-generation Hsp90 inhibitor, acting as both a Hsp90 inhibitor and an antineoplastic agent. It belongs to the classes of resorcinols, benzamides, tertiary carboxamides, isoindoles, and N-alkylpiperazines.

CAS No.912999-49-6
Product NameOnalespib

Biological Targets

HSP90AA1·HSP90AB1

Associated Conditions

non-small cell lung carcinoma·breast carcinoma·breast cancer·neoplasm·triple-negative breast cancer·
* The information provided here is compiled from public sources and is for reference only.