DempoChem Logo
  1. HomeHome
  2. /ProductsProducts
  3. /Bioactive CompoundsBioactive Compounds
  4. /Target & Pathway ModulatorsTarget & Pathway Modulators
  5. /Sigma ReceptorSigma Receptor
  6. /4-(2-((5-Methyl-1-(2-naphthalenyl)-1H-pyrazol-3-yl)oxy)ethyl)morpholineCAS 878141-96-9
Chemical structure of CAS 878141-96-9

4-(2-((5-Methyl-1-(2-naphthalenyl)-1H-pyrazol-3-yl)oxy)ethyl)morpholine

CAS No.878141-96-9
MDL No.MFCD25976945
MFC20H23N3O2
MW337.40
InChI KeyDGPGXHRHNRYVDH-UHFFFAOYSA-N
CUSTOM SYNTHESISPRECLINICAL SUPPORT→

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
- -On RequestOn Request
Custom synthesis and bulk supply options are available upon request.

Product Information

CAS No.878141-96-9
Product Name4-(2-((5-Methyl-1-(2-naphthalenyl)-1H-pyrazol-3-yl)oxy)ethyl)morpholine
Heavy Atom Count25Rotatable Bond Count5
Atom Stereo Count0Bond Stereo Count0
HBA5HBD0
TPSA39.520 ŲCharge0
Exact Mass337.17903Complexity853.02
pKa5.875XLogP3.045

Related Articles

Studies related to this compound and its mechanism of action

Sigma-1 receptors control immune-driven peripheral opioid analgesia during inflammation in mice.

Proceedings of the National Academy of Sciences of the United States of America • Vol. 114, Issue 31 • 2017
PMID: 28716934PMC: PMC5547590DOI: 10.1073/pnas.1620068114

Pharmacological Modulation of the Sigma 1 Receptor and the Treatment of Pain.

Advances in experimental medicine and biology • Vol. 964 • 2017
PMID: 28315267DOI: 10.1007/978-3-319-50174-1_8

Single Doses up to 800 mg of E-52862 Do Not Prolong the QTc Interval--A Retrospective Validation by Pharmacokinetic-Pharmacodynamic Modelling of Electrocardiography Data Utilising the Effects of a Meal on QTc to Demonstrate ECG Assay Sensitivity.

PloS one • Vol. 10, Issue 8 • 2015
PMID: 26291080PMC: PMC4546378DOI: 10.1371/journal.pone.0136369

Modulation of peripheral μ-opioid analgesia by σ1 receptors.

The Journal of pharmacology and experimental therapeutics • Vol. 348, Issue 1 • 2014
PMID: 24155346DOI: 10.1124/jpet.113.208272

Documentation

Similar Products

  • S1RA hydrochloride

    CAS No.1265917-14-3

Your Partner for
Complex Chemistry
logo
  • About Us
  • Perspectives
  • Products
  • Contact
  • Preclinical Development
  • Technologies
  • Custom Synthesis
Ready to start your project?

Provide your target molecule or project specifications to align on a tailored development and scale-up pathway with our scientific team.

START A PROJECT
Westerstraat 10, 3016 DH, Rotterdam, The Netherlands
Westerstraat 10, 3016 DH, Rotterdam, The Netherlands
logo

All products are supplied strictly for research and development use only and are not intended for human or veterinary administration, diagnostic use, or therapeutic use. Preclinical and related services are provided solely for research and development purposes and do not constitute clinical diagnosis, treatment, or veterinary care.

©2026 DempoChem. All Rights Reserved.
DHLFedExUPSPostNL
CLIENT PORTAL|TERMS AND CONDITIONS|PRIVACY POLICY|
  • Products
    • CDMO Compounds
    • API & Candidates
  • Services
    CDMO & Manufacturing
    • Custom Synthesis
    • Process Development
    • Lab To Pilot
    • Commercialization
    • Generic APIs
    CRO
    • Preclinical
    • Pharmacology & Efficacy
    • DMPK & Bioanalysis
    • Toxicology & Safety
    • Disease Models
    Technologies
    • High-Potent
    • Chiral Synthesis
    • Cloud Synthesis
    • Fermentation
    • Flow Chemistry
    • Biocatalysis
    Support
    • Regulatory Support
    • Supply Chain Solutions
  • About
  • Perspectives
  • Contact