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Chemical structure of CAS 875446-37-0

Anacetrapib

CAS No.875446-37-0
MDL No.MFCD16294903
MFC30H25F10NO3
MW637.50
InChI KeyMZZLGJHLQGUVPN-HAWMADMCSA-N

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
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Custom synthesis and bulk supply options are available upon request.

Product Information

CAS No.875446-37-0
Product NameAnacetrapib

Biological Targets

CETP

Associated Conditions

Disorder of lipid metabolism·homozygous familial hypercholesterolemia·coronary artery disease·Hypercholesterolemia·hyperlipidemia·
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

Multiple-dose pharmacodynamics and pharmacokinetics of anacetrapib, a potent cholesteryl ester transfer protein (CETP) inhibitor, in healthy subjects.

Clinical pharmacology and therapeutics • Vol. 84, Issue 6 • 2008
PMID: 18580870DOI: 10.1038/clpt.2008.109

The failure of torcetrapib: what have we learned?

British journal of pharmacology • Vol. 154, Issue 7 • 2008
PMID: 18536741PMC: PMC2492099DOI: 10.1038/bjp.2008.248

Torcetrapib-induced blood pressure elevation is independent of CETP inhibition and is accompanied by increased circulating levels of aldosterone.

British journal of pharmacology • Vol. 154, Issue 7 • 2008
PMID: 18536749PMC: PMC2440088DOI: 10.1038/bjp.2008.229

Anacetrapib: new hope for cholesteryl ester transfer protein inhibitors in the treatment of dyslipidemia.

Nature clinical practice. Cardiovascular medicine • Vol. 5, Issue 6 • 2008
PMID: 18431368DOI: 10.1038/ncpcardio1190

Documentation

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