HomeProductsBioactive CompoundsGPCR & G Protein TargetsGlucagon ReceptorMk-0893
Chemical structure of CAS 870823-12-4

Mk-0893

CAS No.870823-12-4
MDL No.MFCD11616198
MFC32H27Cl2N3O4
MW588.50
InChI KeyDNTVJEMGHBIUMW-IBGZPJMESA-N

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
- -On RequestOn Request
Custom synthesis and bulk supply options are available upon request.

Product Information

CAS No.870823-12-4
Product NameMk-0893

Biological Targets

GCGR

Associated Conditions

type 2 diabetes mellitus
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

Extra-helical binding site of a glucagon receptor antagonist.

Nature • Vol. 533, Issue 7602 • 2016
PMID: 27111510DOI: 10.1038/nature17414

Discovery of a novel glucagon receptor antagonist N-[(4-{(1S)-1-[3-(3, 5-dichlorophenyl)-5-(6-methoxynaphthalen-2-yl)-1H-pyrazol-1-yl]ethyl}phenyl)carbonyl]-β-alanine (MK-0893) for the treatment of type II diabetes.

Journal of medicinal chemistry • Vol. 55, Issue 13 • 2012
PMID: 22708876DOI: 10.1021/jm300579z

Documentation