HomeProductsBuilding BlocksHeterocyclic ScaffoldsIndolesOC-000459
Chemical structure of CAS 851723-84-7

OC-000459

CAS No.851723-84-7
MDL No.MFCD18633254
MFC21H17FN2O2
MW348.40
InChI KeyFATGTHLOZSXOBC-UHFFFAOYSA-N
CUSTOM SYNTHESIS

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
- -On RequestOn Request
Custom synthesis and bulk supply options are available upon request.

Product Information

CAS No.851723-84-7
Product NameOC-000459

Biological Targets

PTGDR2

Associated Conditions

atopic eczema·eosinophilic esophagitis·allergic rhinitis·asthma
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

The IUPHAR Guide to Immunopharmacology: connecting immunology and pharmacology.

Immunology • Vol. 160, Issue 1 • 2020
PMID: 32020584PMC: PMC7160657DOI: 10.1111/imm.13175

Heightened response of eosinophilic asthmatic patients to the CRTH2 antagonist OC000459.

Allergy • Vol. 69, Issue 9 • 2014
PMID: 24866478DOI: 10.1111/all.12451

Pharmacologic profile of OC000459, a potent, selective, and orally active D prostanoid receptor 2 antagonist that inhibits mast cell-dependent activation of T helper 2 lymphocytes and eosinophils.

The Journal of pharmacology and experimental therapeutics • Vol. 340, Issue 2 • 2012
PMID: 22106101DOI: 10.1124/jpet.111.187203

Documentation