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Chemical structure of CAS 849675-66-7

Encequidar

CAS No.849675-66-7
MDL No.MFCD25976625
MFC38H36N6O7
MW688.70
InChI KeyAHJUHHDDCJQACA-UHFFFAOYSA-N
CUSTOM SYNTHESISPRECLINICAL SUPPORT

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
- -On RequestOn Request
Custom synthesis and bulk supply options are available upon request.

Product Information

CAS No.849675-66-7
Product NameEncequidar

Biological Targets

ABCB1

Associated Conditions

breast cancer·neoplasm·angiosarcoma·breast neoplasm
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

Discovery of Encequidar, First-in-Class Intestine Specific P-glycoprotein Inhibitor.

Journal of medicinal chemistry • Vol. 64, Issue 7 • 2021
PMID: 33729781DOI: 10.1021/acs.jmedchem.0c01826

Tolerability and pharmacokinetics of a new P-glycoprotein inhibitor, HM30181, in healthy Korean male volunteers: single- and multiple-dose randomized, placebo-controlled studies.

Clinical therapeutics • Vol. 34, Issue 2 • 2012
PMID: 22284902DOI: 10.1016/j.clinthera.2012.01.003

Selective inhibition of MDR1 (ABCB1) by HM30181 increases oral bioavailability and therapeutic efficacy of paclitaxel.

European journal of pharmacology • Vol. 627, Issue 1-3 • 2010
PMID: 19903471DOI: 10.1016/j.ejphar.2009.11.008

Response of brain specific microenvironment to P-glycoprotein inhibitor: an important factor determining therapeutic effect of P-glycoprotein inhibitor on brain metastatic tumors.

International journal of oncology • Vol. 33, Issue 4 • 2008
PMID: 18813783

Documentation

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