CAS 848695-25-0 – (6-Chloro-9-(4-methoxy-3,5-dimethylpyridin…

Pack Size	Purity	Price	Availability	Action
-	-	On Request	On Request
Custom synthesis and bulk supply options are available upon request.

Product Information

BIIB021 is a 2-aminopurine with a chlorine at position 6 and a (4-methoxy-3,5-dimethylpyridin-2-yl)methyl group at position 9. It functions as an Hsp90 inhibitor and antineoplastic agent. It belongs to the classes of pyridines, 2-aminopurines, organochlorine compounds, and aromatic ethers.

CAS No.	848695-25-0
Product Name	(6-Chloro-9-(4-methoxy-3,5-dimethylpyridin-2-ylmethyl)-9H-purin-2-yl)amine

Irritant

Signal Word:Warning

HCode:H315-H319-H335

PCode:P261-P264-P264+P265-P271-P280-P302+P352-P304+P340-P305+P351+P338-P319-P321-P332+P317-P337+P317-P362+P364-P403+P233-P405-P501

CAS No.	848695-25-0
MDL No.	N/A
MF	C₁₄H₁₅ClN₆O
MW	318.76
InChI Key	QULDDKSCVCJTPV-UHFFFAOYSA-N

(6-Chloro-9-(4-methoxy-3,5-dimethylpyridin-2-ylmethyl)-9H-purin-2-yl)amine

Pricing & Availability

Product Information

Safety Information

Properties

Documentation

(6-Chloro-9-(4-methoxy-3,5-dimethylpyridin-2-ylmethyl)-9H-purin-2-yl)amine

Pricing & Availability

Product Information

Safety Information

Properties

Related Articles

Correlation between chemotype-dependent binding conformations of HSP90α/β and isoform selectivity-Implications for the structure-based design of HSP90α/β selective inhibitors for treating neurodegenerative diseases.

In vitro metabolism of BIIB021, an inhibitor of heat shock protein 90, in liver microsomes and hepatocytes of rats, dogs, and humans and recombinant human cytochrome P450 isoforms.

An investigation into the potential use of serum Hsp70 as a novel tumour biomarker for Hsp90 inhibitors.

Heat shock protein 90 inhibitor BIIB021 (CNF2024) depletes NF-kappaB and sensitizes Hodgkin's lymphoma cells for natural killer cell-mediated cytotoxicity.

Documentation