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Chemical structure of CAS 839713-36-9

Nelotanserin

CAS No.839713-36-9
MDL No.MFCD16619341
MFC18H15BrF2N4O2
MW437.20
InChI KeyCOSPVUFTLGQDQL-UHFFFAOYSA-N
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Product Information

CAS No.839713-36-9
Product NameNelotanserin

Biological Targets

HTR2A

Associated Conditions

Hallucinations·sleep-wake disorder·Lewy body dementia·insomnia
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

Serotonin control of sleep-wake behavior.

Sleep medicine reviews • Vol. 15, Issue 4 • 2011
PMID: 21459634DOI: 10.1016/j.smrv.2010.11.003

Discovery of 1-[3-(4-bromo-2-methyl-2h-pyrazol-3-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea (nelotanserin) and related 5-hydroxytryptamine2A inverse agonists for the treatment of insomnia.

Journal of medicinal chemistry • Vol. 53, Issue 5 • 2010
PMID: 20143782DOI: 10.1021/jm9007328

Nelotanserin, a novel selective human 5-hydroxytryptamine2A inverse agonist for the treatment of insomnia.

The Journal of pharmacology and experimental therapeutics • Vol. 332, Issue 1 • 2010
PMID: 19841476DOI: 10.1124/jpet.109.160994

Documentation

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