Cariprazine is an N-alkylpiperazine with an N,N-dimethyl-N'-{trans-4-[2-(piperazin-1-yl)ethyl]cyclohexyl}urea structure, substituted at position 4 of the piperazine ring with a 2,3-dichlorophenyl group. It is used as the hydrochloride salt for treating schizophrenia and bipolar disorder. It acts as a dopamine agonist, a second-generation antipsychotic, and a serotonergic antagonist. It belongs to the classes of ureas, N-alkylpiperazines, N-arylpiperazines, and dichlorobenzenes. It is the conjugate base of cariprazine(1+).
