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Chemical structure of CAS 83891-03-6

Norfluoxetine

In Stock•Starting at $46 for 25 mg•Purity ≥ 95%
CAS No.83891-03-6
MDL No.N/A
MFC16H16F3NO
MW295.30
InChI KeyWIQRCHMSJFFONW-UHFFFAOYSA-N
CUSTOM SYNTHESISPRECLINICAL SUPPORT

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
25 mg95%$46In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

Norfluoxetine is a (trifluoromethyl)benzene derivative.

CAS No.83891-03-6
Product NameNorfluoxetine
Heavy Atom Count21Rotatable Bond Count5
Atom Stereo Count1Bond Stereo Count0
HBA2HBD1
TPSA35.250 ŲCharge0
Exact Mass295.11840Complexity551.98
pKa7.130XLogP4.174

Related Articles

Studies related to this compound and its mechanism of action

Inhibition of the human two-pore domain potassium channel, TREK-1, by fluoxetine and its metabolite norfluoxetine.

British journal of pharmacology • Vol. 144, Issue 6 • 2005
PMID: 15685212PMC: PMC1576064DOI: 10.1038/sj.bjp.0706068

Expression, purification, biochemical characterization, and comparative function of human cytochrome P450 2D6.1, 2D6.2, 2D6.10, and 2D6.17 allelic isoforms.

The Journal of pharmacology and experimental therapeutics • Vol. 303, Issue 3 • 2002
PMID: 12438554DOI: 10.1124/jpet.102.039891

Cytochrome P450 2D6.1 and cytochrome P450 2D6.10 differ in catalytic activity for multiple substrates.

Pharmacogenetics • Vol. 11, Issue 6 • 2001
PMID: 11505218DOI: 10.1097/00008571-200108000-00003

Effects of norfluoxetine, the major metabolite of fluoxetine, on the cloned neuronal potassium channel Kv3.1.

Neuropharmacology • Vol. 41, Issue 4 • 2001
PMID: 11543764DOI: 10.1016/s0028-3908(01)00088-0

Documentation

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