Obatoclax
In Stock•Starting at $109 for 25 mg•Purity ≥ 98%
| CAS No. | 803712-67-6 |
|---|---|
| MDL No. | N/A |
| MF | C20H19N3O |
| MW | 317.40 |
| InChI Key | CVCLJVVBHYOXDC-IAZSKANUSA-N |
| CAS No. | 803712-67-6 |
|---|---|
| MDL No. | N/A |
| MF | C20H19N3O |
| MW | 317.40 |
| InChI Key | CVCLJVVBHYOXDC-IAZSKANUSA-N |
| Pack Size | Purity | Price | Availability | Action |
|---|---|---|---|---|
| 25 mg | 98% | $109 | In Stock | |
| 50 mg | 98% | $168 | In Stock | |
| 100 mg | 98% | $276 | In Stock | |
| Custom synthesis and bulk supply options are available upon request. | ||||
Obatoclax is a small molecule pan-inhibitor of Bcl-2 family proteins with pro-apoptotic activity. GX015-070 is a selective antagonist of the BH3-binding groove of Bcl-2 family proteins, which are frequently overexpressed in cancers such as chronic lymphocytic leukemia (CLL). It induces or restores apoptosis in cancer cells by inhibiting multiple apoptosis suppressors within the Bcl-2 family. (NCIt)
| CAS No. | 803712-67-6 |
|---|---|
| Product Name | Obatoclax |
| Heavy Atom Count | 24 | Rotatable Bond Count | 2 |
| Atom Stereo Count | 0 | Bond Stereo Count | 2 |
| HBA | 2 | HBD | 2 |
| TPSA | 53.170 Ų | Charge | 0 |
| Exact Mass | 317.15281 | Complexity | 1125.42 |
| pKa | 5.875 | XLogP | 1.019 |