HomeProductsBioactive CompoundsCell CycleCDKRGB-286638 free base
Chemical structure of CAS 784210-88-4

RGB-286638 free base

In Stock•Starting at $62 for 5 mg•Purity ≥ 98%
CAS No.784210-88-4
MDL No.MFCD18633230
MFC29H35N7O4
MW545.60
InChI KeyXLSYZSRXVVCHLS-UHFFFAOYSA-N
CUSTOM SYNTHESISPRECLINICAL SUPPORT

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
5 mg98%$62In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

CAS No.784210-88-4
Product NameRGB-286638 free base

Biological Targets

CDK1·CDK2·CDK4·CDK5·CDK7·

Associated Conditions

lymphoid neoplasm
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

Phase I study of RGB-286638, a novel, multitargeted cyclin-dependent kinase inhibitor in patients with solid tumors.

Clinical cancer research : an official journal of the American Association for Cancer Research • Vol. 20, Issue 18 • 2014
PMID: 25024258DOI: 10.1158/1078-0432.CCR-14-0325

Small-molecule multi-targeted kinase inhibitor RGB-286638 triggers P53-dependent and -independent anti-multiple myeloma activity through inhibition of transcriptional CDKs.

Leukemia • Vol. 27, Issue 12 • 2013
PMID: 23807770PMC: PMC3928098DOI: 10.1038/leu.2013.194

Documentation

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