CHF5074 reduces biomarkers of neuroinflammation in patients with mild cognitive impairment: a 12-week, double-blind, placebo-controlled study.
Current Alzheimer research • Vol. 10, Issue 7 • 2013
Therapeutic effect of CHF5074, a new γ-secretase modulator, in a mouse model of scrapie.
Prion • Vol. 6, Issue 1 • 2012
Discovery of 4-aminomethylphenylacetic acids as γ-secretase modulators via a scaffold design approach.
Bioorganic & medicinal chemistry letters • Vol. 21, Issue 24 • 2011
The γ-secretase modulator CHF5074 reduces the accumulation of native hyperphosphorylated tau in a transgenic mouse model of Alzheimer's disease.
Journal of molecular neuroscience : MN • Vol. 45, Issue 1 • 2011
