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Chemical structure of CAS 69756-53-2

Halofantrine

CAS No.69756-53-2
MDL No.N/A
MFC26H30Cl2F3NO
MW500.40
InChI KeyFOHHNHSLJDZUGQ-UHFFFAOYSA-N

Pricing & Availability

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Product Information

3-(Dibutylamino)-1-[1,3-dichloro-6-(trifluoromethyl)-9-phenanthrenyl]propan-1-ol is a phenanthrene derivative.

CAS No.69756-53-2
Product NameHalofantrine

Associated Conditions

malaria
* The information provided here is compiled from public sources and is for reference only.

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Studies related to this compound and its mechanism of action

The activities of current antimalarial drugs on the life cycle stages of Plasmodium: a comparative study with human and rodent parasites.

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In vitro susceptibility of Plasmodium falciparum to monodesethylamodiaquine, quinine, mefloquine and halofantrine in Abidjan (Côte d'Ivoire).

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Candidate selection and preclinical evaluation of N-tert-butyl isoquine (GSK369796), an affordable and effective 4-aminoquinoline antimalarial for the 21st century.

Journal of medicinal chemistry • Vol. 52, Issue 5 • 2009
PMID: 19222165DOI: 10.1021/jm8012618

The crystal structure of halofantrine-ferriprotoporphyrin IX and the mechanism of action of arylmethanol antimalarials.

Journal of inorganic biochemistry • Vol. 102, Issue 8 • 2008
PMID: 18508124DOI: 10.1016/j.jinorgbio.2008.04.001

Documentation

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