HomeProductsBioactive CompoundsPI3K/Akt/mTOR PathwayPI3KTG-100115
Chemical structure of CAS 677297-51-7

TG-100115

CAS No.677297-51-7
MDL No.MFCD16038873
MFC18H14N6O2
MW346.30
InChI KeyUJIAQDJKSXQLIT-UHFFFAOYSA-N

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
- -On RequestOn Request
Custom synthesis and bulk supply options are available upon request.

Product Information

3-[2,4-Diamino-7-(3-hydroxyphenyl)-6-pteridinyl]phenol is a pteridine compound.

CAS No.677297-51-7
Product NameTG-100115

Biological Targets

PIK3CD·PIK3CG

Associated Conditions

myocardial infarction
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

Identification of TG100-115 as a new and potent TRPM7 kinase inhibitor, which suppresses breast cancer cell migration and invasion.

Biochimica et biophysica acta. General subjects • Vol. 1861, Issue 4 • 2017
PMID: 28161478DOI: 10.1016/j.bbagen.2017.01.034

Comprehensive analysis of kinase inhibitor selectivity.

Nature biotechnology • Vol. 29, Issue 11 • 2011
PMID: 22037378DOI: 10.1038/nbt.1990

Activation state-dependent binding of small molecule kinase inhibitors: structural insights from biochemistry.

Chemistry & biology • Vol. 17, Issue 11 • 2010
PMID: 21095574DOI: 10.1016/j.chembiol.2010.09.010

Aerosolized phosphoinositide 3-kinase gamma/delta inhibitor TG100-115 [3-[2,4-diamino-6-(3-hydroxyphenyl)pteridin-7-yl]phenol] as a therapeutic candidate for asthma and chronic obstructive pulmonary disease.

The Journal of pharmacology and experimental therapeutics • Vol. 328, Issue 3 • 2009
PMID: 19056934DOI: 10.1124/jpet.108.144311

Documentation

Similar Products