Product Information

FK-866 is a benzamide and an N-acylpiperidine.

CAS No.	658084-64-1
Product Name	Daporinad

Irritant

Signal Word:Warning

HCode:H302-H315-H319-H335

PCode:P264-P270-P301+P317-P330-P501-P261-P264+P265-P271-P280-P302+P352-P304+P340-P305+P351+P338-P319-P321-P332+P317-P337+P317-P362+P364-P403+P233-P405

Studies related to this compound and its mechanism of action

Targeting the NAD salvage pathway suppresses APC mutation-driven colorectal cancer growth and Wnt/β-catenin signaling via increasing Axin level.

Cell communication and signaling : CCS • Vol. 18, Issue 1 • 2020

PMID: 32005247 PMC: PMC6995173 DOI: 10.1186/s12964-020-0513-5

Inhibition of nicotinamide phosphoribosyltransferase and depletion of nicotinamide adenine dinucleotide contribute to arsenic trioxide suppression of oral squamous cell carcinoma.

Toxicology and applied pharmacology • Vol. 331 • 2017

PMID: 28501332 PMC: PMC5568507 DOI: 10.1016/j.taap.2017.05.008

Retinal toxicity, in vivo and in vitro, associated with inhibition of nicotinamide phosphoribosyltransferase.

Toxicological sciences : an official journal of the Society of Toxicology • Vol. 144, Issue 1 • 2015

PMID: 25505128 DOI: 10.1093/toxsci/kfu268

On-target effect of FK866, a nicotinamide phosphoribosyl transferase inhibitor, by apoptosis-mediated death in chronic lymphocytic leukemia cells.

Clinical cancer research : an official journal of the American Association for Cancer Research • Vol. 20, Issue 18 • 2014

PMID: 25172933 DOI: 10.1158/1078-0432.CCR-14-0624

Daporinad

CAS No.	658084-64-1
MDL No.	N/A
MF	C₂₄H₂₉N₃O₂
MW	391.50
InChI Key	KPBNHDGDUADAGP-VAWYXSNFSA-N

CUSTOM SYNTHESIS

Pricing & Availability

Pack Size	Purity	Price	Availability	Action
-	-	On Request	On Request
Custom synthesis and bulk supply options are available upon request.

Product Information

FK-866 is a benzamide and an N-acylpiperidine.

CAS No.	658084-64-1
Product Name	Daporinad

Irritant

Signal Word:Warning

HCode:H302-H315-H319-H335

PCode:P264-P270-P301+P317-P330-P501-P261-P264+P265-P271-P280-P302+P352-P304+P340-P305+P351+P338-P319-P321-P332+P317-P337+P317-P362+P364-P403+P233-P405

Daporinad

Pricing & Availability

Product Information

Safety Information

Properties

Daporinad

Pricing & Availability

Product Information

Safety Information

Properties

Documentation

Daporinad

Pricing & Availability

Product Information

Safety Information

Properties

Related Articles

Targeting the NAD salvage pathway suppresses APC mutation-driven colorectal cancer growth and Wnt/β-catenin signaling via increasing Axin level.

Inhibition of nicotinamide phosphoribosyltransferase and depletion of nicotinamide adenine dinucleotide contribute to arsenic trioxide suppression of oral squamous cell carcinoma.

Retinal toxicity, in vivo and in vitro, associated with inhibition of nicotinamide phosphoribosyltransferase.

On-target effect of FK866, a nicotinamide phosphoribosyl transferase inhibitor, by apoptosis-mediated death in chronic lymphocytic leukemia cells.

Similar Products

(E)-N-(4-(1-(3-Aminobenzoyl)piperidin-4-YL)butyl)-3-(pyridin-3-YL)acrylamide

Daporinad

Pricing & Availability

Product Information

Safety Information

Properties

Related Articles

Targeting the NAD salvage pathway suppresses APC mutation-driven colorectal cancer growth and Wnt/β-catenin signaling via increasing Axin level.

Inhibition of nicotinamide phosphoribosyltransferase and depletion of nicotinamide adenine dinucleotide contribute to arsenic trioxide suppression of oral squamous cell carcinoma.

Retinal toxicity, in vivo and in vitro, associated with inhibition of nicotinamide phosphoribosyltransferase.

On-target effect of FK866, a nicotinamide phosphoribosyl transferase inhibitor, by apoptosis-mediated death in chronic lymphocytic leukemia cells.

Similar Products

(E)-N-(4-(1-(3-Aminobenzoyl)piperidin-4-YL)butyl)-3-(pyridin-3-YL)acrylamide

Documentation