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Chemical structure of CAS 641571-10-0

Nilotinib

CAS No.641571-10-0
MDL No.MFCD09833716
MFC28H22F3N7O
MW529.50
InChI KeyHHZIURLSWUIHRB-UHFFFAOYSA-N

Pricing & Availability

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Product Information

Nilotinib is a (trifluoromethyl)benzene, pyrimidine, pyridine, and imidazole derivative, classified as a secondary amino compound and secondary carboxamide. It functions as an antineoplastic agent, tyrosine kinase inhibitor, and anticoronaviral agent.

CAS No.641571-10-0
Product NameNilotinib
Health HazardHealth Hazard
Environmental HazardEnvironmental Hazard
Signal Word:Danger
HCode:H361-H372-H373-H400-H410-H413
PCode:P203-P260-P264-P270-P273-P280-P318-P319-P391-P405-P501

Related Articles

Studies related to this compound and its mechanism of action

The small molecule tyrosine kinase inhibitor AMN107 inhibits TEL-PDGFRbeta and FIP1L1-PDGFRalpha in vitro and in vivo.

Blood • Vol. 106, Issue 9 • 2005
PMID: 16030188PMC: PMC1895333DOI: 10.1182/blood-2005-05-1932

AMN107: tightening the grip of imatinib.

Cancer cell • Vol. 7, Issue 2 • 2005
PMID: 15710324DOI: 10.1016/j.ccr.2005.01.020

Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl.

Cancer cell • Vol. 7, Issue 2 • 2005
PMID: 15710326DOI: 10.1016/j.ccr.2005.01.007

After imatinib: new hopes for chronic myeloid leukaemia.

Drug discovery today • Vol. 10, Issue 8 • 2005
PMID: 15837592DOI: 10.1016/S1359-6446(05)03422-7

Documentation

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