HomeProductsBioactive CompoundsGPCR & G Protein TargetsP2Y ReceptorDiquafosol
Chemical structure of CAS 59985-21-6

Diquafosol

CAS No.59985-21-6
MDL No.N/A
MFC18H26N4O23P4
MW790.30
InChI KeyNMLMACJWHPHKGR-NCOIDOBVSA-N

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
- -On RequestOn Request
Custom synthesis and bulk supply options are available upon request.

Product Information

P(1),P(4)-bis(uridin-5'-yl) tetraphosphate is a pyrimidine ribonucleoside 5'-tetraphosphate with 5'-uridinyl residues at the P(1) and P(4) positions. It functions as a P2Y2 receptor agonist and is a mouse metabolite. It is also a uridine 5'-phosphate.

CAS No.59985-21-6
Product NameDiquafosol

Biological Targets

P2RY1·P2RY2·P2RY4·P2RY6

Associated Conditions

eye disease·dry eye syndrome
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

P2Y(2) receptor agonists: a new class of medication targeted at improved mucociliary clearance.

Chest • Vol. 121, Issue 5 Suppl • 2002
PMID: 12010852DOI: 10.1378/chest.121.5_suppl.201s

Pharmacology of INS37217 [P(1)-(uridine 5')-P(4)- (2'-deoxycytidine 5')tetraphosphate, tetrasodium salt], a next-generation P2Y(2) receptor agonist for the treatment of cystic fibrosis.

The Journal of pharmacology and experimental therapeutics • Vol. 302, Issue 3 • 2002
PMID: 12183642DOI: 10.1124/jpet.102.035485

INS365 suppresses loss of corneal epithelial integrity by secretion of mucin-like glycoprotein in a rabbit short-term dry eye model.

Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics • Vol. 18, Issue 4 • 2002
PMID: 12222766DOI: 10.1089/10807680260218524

Inhaled P2Y2 receptor agonists as a treatment for patients with Cystic Fibrosis lung disease.

Advanced drug delivery reviews • Vol. 54, Issue 11 • 2002
PMID: 12458155DOI: 10.1016/s0169-409x(02)00154-0

Documentation

Similar Products