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Chemical structure of CAS 59456-70-1

Nikkomycin Z

In Stock•Starting at $426 for 1 mg
CAS No.59456-70-1
MDL No.N/A
MFC20H25N5O10
MW495.40
InChI KeyWWJFFVUVFNBJTN-VHDFTHOZSA-N
CUSTOM SYNTHESISPRECLINICAL SUPPORT

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
1 mgTo Be Confirmed$426In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

Nikkomycin Z is a uridine-based nucleoside-peptide antibiotic that inhibits fungal chitin biosynthesis by targeting chitin synthase. It functions as an antifungal agent and is related to uridine.

CAS No.59456-70-1
Product NameNikkomycin Z

Associated Conditions

coccidioidomycosis
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

Discovery of novel antifungal (1,3)-beta-D-glucan synthase inhibitors.

Antimicrobial agents and chemotherapy • Vol. 44, Issue 2 • 2000
PMID: 10639364PMC: PMC89685DOI: 10.1128/AAC.44.2.368-377.2000

Drug interaction studies of a glucan synthase inhibitor (LY 303366) and a chitin synthase inhibitor (Nikkomycin Z) for inhibition and killing of fungal pathogens.

Antimicrobial agents and chemotherapy • Vol. 44, Issue 9 • 2000
PMID: 10952614PMC: PMC90104DOI: 10.1128/AAC.44.9.2547-2548.2000

In vitro antifungal activity of nikkomycin Z in combination with fluconazole or itraconazole.

Antimicrobial agents and chemotherapy • Vol. 43, Issue 6 • 1999
PMID: 10348760PMC: PMC89286DOI: 10.1128/AAC.43.6.1401

Efficacy of nikkomycin Z in the treatment of murine histoplasmosis.

Antimicrobial agents and chemotherapy • Vol. 42, Issue 9 • 1998
PMID: 9736565PMC: PMC105835DOI: 10.1128/AAC.42.9.2371

Documentation

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